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Analysed 28,199 tweets, tweets from the last 205 weeks.
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Last 50 tweets from @VPrasadMDMPH
 
 
In reply to @CatieOldenburg
IMHO the comment about co-authors I think is a commentary on what a PITA submission systems are. Certainly would never not include someone on a paper bc I am lazy! I tend to publish paper w very long author lists.
Replying to @CatieOldenburg
That was a bizarre interpretation of my thread
 
In reply to @DrToddLee
This is such a cool research idea. Congrats!
 
Wise points by Manni
US FDA has the legal authority to enforce these standards, but keeps falling short
Ht @AaronGoodman33
This is how studies for multiply relapsed #mmsm should be.

Control= physicians choice
Endpoint= OS

Results?- new agent often fails spectacularly as Selinexor did here.

Here’s why randomization, fair controls and appropriate endpoints are necessary.

bit.ly/3flXqC8 pic.twitter.com/RmE67Nrwta
 
Si tu mentor no publicó 10 papers en el último año, entonces tanto tú como él necesitan otro mentor

Consejos de @VPrasadMDMPH sobre proceso de #peereview y publicaciones biomedicas

youtu.be/PmcQNvm1Os4
 
Journalists need to stop with the:
"Important person X has tested positive for COVID even after being vaccinated."
In the next 20 years we are going to have innumerable positive tests in asymptomatic people or people with colds. This is not news and does harm.
 
 
1- Have perspective, 2- avoid groupthink, 3- exercise. Got it!
 
How I deal with the haters

By request, my new video
youtu.be/4mYObYppR1c
 
If your goal is increasing vaccination, you might want to tone down the fear-mongering speculation
 
New paper by JPAI
If you think his original stat commentary w/ the theme of "there is massive uncertainty" actually "predicted" 10k deaths, then this paper is not at the right reading level for you!

It's insightful & probably spot on 👇
link.springer.com/content/pdf/10…
 
Some good points about publishing from someone who has done a lot in and for the field. Honestly, advice like this is hard to find!!
 
 
So are we supposed to just not credit our collaborators or?
Replying to @AlainnaJJ
Only the ones who can't detect humor
 
In reply to @robyn_s_lee
Or follow your organization’s or ICMJE’s objective authorship criteria. Excluding people who deserve authorship because you’re too lazy to input their names is unethical.
what about just excluding the ones without ability to detect humor?
 
A. Totally worth 3 minutes of your time - don't take it too seriously.
B. Congrats VP, proud to have collaborated on a few of them.
 
In reply to @VPrasadMDMPH
Turned it into a video for those interested youtu.be/PmcQNvm1Os4
Replying to @VPrasadMDMPH
25. Uh oh, years of cutting off authors past 4 has caught up with me!! Sorry, I thought your name was Et. al. Poor sense of humor & poor reading comprehension!
 
In reply to @VPrasadMDMPH
24. If you didn't find this funny, then you are doomed; sorry to say But jokes aside, if anyone wants sincere advice contact me here vinayakkprasad.com/contact
Replying to @VPrasadMDMPH
Turned it into a video for those interested youtu.be/PmcQNvm1Os4
 
In reply to @VPrasadMDMPH
Have you talked about this NEJM article regarding decreased single-dose efficacy against delta? nejm.org/doi/full/10.10…
Replying to @KC_Allergy_Doc
there are a few different data sets, imo the q is what is the effectiveness of 1 dose among kids in this age group from getting severely ill and whether the added benefit of D2 is worth the added risk of myocarditis to lower that risk.
 
In reply to @VPrasadMDMPH
Vinay, what are your thoughts on this from Dr. Offit? "The choice to avoid an mRNA vaccine in order to avoid myocarditis ignores the fact that both covid and MIS-C cause myocarditis, and far more commonly. There are no risk-free choices.” - Dr. Paul Offit
Replying to @KC_Allergy_Doc
how about 1 dose mrna? his quote is 2 or nothing and I would quantify it, as I did in a video a while back
 
Controversies in Leukemia

50 year old newly diagnosed AML with highly complex karyotype including 17p deletion. NGS with TP53 mutation. Patient is fit. He is not able to travel to a center with clinical trials. WBC 9, Hb 7, Plt 15,ANC 200.

Your induction recommendation?
Replying to @AaronGoodman33
Finally one of your polls that is trending right!! For now
 
In reply to @VPrasadMDMPH
This is so frustrating. One should be able to look at this and easily see what the rate of myocarditis is in boys 12-15 and 16-17 after dose 1 and 2 but I can't find it anywhere. Do you see it? Isn't that what we all want to know?
Replying to @TracyBethHoeg
I can't find it anywhere That's bad form from CDC
 
In reply to @VPrasadMDMPH
This is so frustrating. One should be able to look at this and easily see what the rate of myocarditis is in boys 12-15 and 16-17 after dose 1 and 2 but I can't find it anywhere. Do you see it? Isn't that what we all want to know?
 
In reply to @VPrasadMDMPH
Its bad that they don't break this down by sex Its bad this is prelim data, and we don't have confirmed estimates Its bad we don't know how many post D2 vs. D1 There is no reason we shouldn't have this info in real time
Replying to @VPrasadMDMPH
Vaccination is marvelous for older people (like me!), the reason so many people are so interested in precise numbers is that as age falls, the benefit/ harm balance gets tenuous Numeracy required
 
CDC update July 16, 2021
Among kids 12-17
1 in 22k have myocarditis (risk not broken down M vs F)
1 in 2500 hospitalized for any reason

The benefits/ harm balance must be carefully assessed in 5-11 yo, and notably UK not recommending vax in healthy <18

cdc.gov/mmwr/volumes/7… pic.twitter.com/zX1uoKdlVb
Replying to @VPrasadMDMPH
Its bad that they don't break this down by sex Its bad this is prelim data, and we don't have confirmed estimates Its bad we don't know how many post D2 vs. D1 There is no reason we shouldn't have this info in real time
 
CDC update July 16, 2021
Among kids 12-17
1 in 22k have myocarditis (risk not broken down M vs F)
1 in 2500 hospitalized for any reason

The benefits/ harm balance must be carefully assessed in 5-11 yo, and notably UK not recommending vax in healthy <18

cdc.gov/mmwr/volumes/7…
 
In reply to @VPrasadMDMPH
Make this your 301st article..
 
In reply to @VPrasadMDMPH
Work with @ManniMD1 and you will get to 300 fast.
Ahh. Manni will get there years before I did. No fair. Younger generations are smarter
 
I just passed the 200 mark (1st woman in my dept to do so 😳) and this is 💯 on point
 
“Sociology suggests that pundits and policy makers have been looking at vaccine refusal all wrong: It’s not an individual problem, but a social one.”

theatlantic.com/ideas/archive/…
 
Amazing words of truth in regard to academic publication. Some of it is a little tongue in cheek, but this thread is chock full of big juicy pearls! @UChicagoMed @UChicagoPCCM @UCSFimaging @KURadiology @UWRadiology @UChicagoRADS
 
This almost read like the “House of God Rules of Publishing Papers”. Points 7, 9 and 10 are so true!
 
In reply to @VPrasadMDMPH
Couldn't do trials; randomizing to "coffee grinding allowed" would be unethical.
Replying to @WesPegden
No equipoise for parachutes
 
In reply to @VPrasadMDMPH
You can keep cranking up the pressure, but I strongly suspect you won't increase your vaccination rate by more than 5 % and the negative social consequences from firing people may outweigh the gains. Policy is more than slogans
Replying to @VPrasadMDMPH
One more addendum: drawing analogy to a public health interventions that took years or decades to increase compliance is silly Here you need compliance increased in days to weeks. In years will be a moot pt.
 
In reply to @VPrasadMDMPH
In the pediatric population, public school mandates with onerous opt outs increase vax rates. And parents are far more protective of their kids than they are of themselves. Not sure what’s informing your priors. pediatrics.aappublications.org/content/138/3/…
Replying to @seanmmcbride
None of that is extrapolatable The 2 most critical points. You need this to occur on the order of weeks to months not years and decades. The USA today is not what it was.
 
In reply to @VPrasadMDMPH
Some people saying the punishment will be a fine... Ok, I suspect many will just pay the fine. Others saying it works for kindergartners. Something tells me that doesn't extrapolate to 50 year olds
Replying to @VPrasadMDMPH
You can keep cranking up the pressure, but I strongly suspect you won't increase your vaccination rate by more than 5 % and the negative social consequences from firing people may outweigh the gains. Policy is more than slogans
 
In reply to @VPrasadMDMPH
I thought your point was that guns were a risk in imposing public measures. Sorry if I misunderstood.
You cited measures that are not enforced with any vigor. My understanding of the essay is that they want these measures to be enforced with vigor, which is risky
 
In reply to @VPrasadMDMPH
I just wish folks could think through their policy ideas. What specifically would you do? How would you enforce it? What might ensue? This is policy 101
Replying to @VPrasadMDMPH
Some people saying the punishment will be a fine... Ok, I suspect many will just pay the fine. Others saying it works for kindergartners. Something tells me that doesn't extrapolate to 50 year olds
 
In reply to @VPrasadMDMPH
How do you not know that children must have multiple vaccinations before entering kindergarten?
Replying to @flyosity
Turns out that's not going to solve this problem. Some Americans little older than kindergarten matriculants next fall.
 
In reply to @pafournier
And also get the flu vaccine.
None of those things are totally true Seat belts took decades of persuasion, and if you choose to go unbuckled see how long before you get caught Traffic violations common/ speeding is the norm Smoking continues Flu vaccine uptake is still poor
 
Despite setbacks due to delta, we are finally poised to reopen our schools in California and return 6 million children to normal daily routines. And this time, we have our health officials on board.
sfchronicle.com/bayarea/articl…
 
In reply to @VPrasadMDMPH
This time the fat tail risk is what the response will be.
Replying to @VPrasadMDMPH
I just wish folks could think through their policy ideas. What specifically would you do? How would you enforce it? What might ensue? This is policy 101
 
In reply to @VPrasadMDMPH
I'm gonna take a wild guess and assume that most of our nation's 300 million guns are in the hands of people who don't want to vaccinate.
 
In reply to @VPrasadMDMPH
I would love it if someone who offers strong arm tactics walks me through their thinking about what happens next in a volatile nation with 300 million guns
Replying to @VPrasadMDMPH
This time the fat tail risk is what the response will be.
 
So after we throw unvaccinated people out of school and college, ban them from restaurants & bars, fire them from private and federal employment, the next step is to round them up and put them in prison?

Hmmm what would that do for viral spread?

washingtonpost.com/opinions/2021/…
Replying to @VPrasadMDMPH
I would love it if someone who offers strong arm tactics walks me through their thinking about what happens next in a volatile nation with 300 million guns
 
So after we throw unvaccinated people out of school and college, ban them from restaurants & bars, fire them from private and federal employment, the next step is to round them up and put them in prison?

Hmmm what would that do for viral spread?

washingtonpost.com/opinions/2021/…
 
In reply to @VPrasadMDMPH
The John Snow move of the West Coast - coffee is crucial
Replying to @drkevinknopf
Hahaha. Thankfully I have a grinder. But that's a cold move
 
It's been surpassed by a new criticism: we don't have equipoise.
If major professional societies have different guidelines, and there are two ongoing cluster randomized trials. What do you think that means for equipoise?
The most delusion response to my piece is claiming the evidence supporting vaccinated people wearing cloth masks if cases >50 per 100k SUMMED over 7 days, but not less than that is actually strong!!

I missed when Moses descended with that cutoff value!

medpagetoday.com/opinion/vinay-…
 
At the peak of covid last year, I noticed a couple grocery stores did not allow you to grind your coffee in their coffee grinder before taking it home. They taped it off like playgrounds.

Just two obviously beneficial interventions
 
 
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